Christopher B Newgard: search on Z-Library

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1

Mechanisms of disease: Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

Muoio, Deborah M., Newgard, Christopher B.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2008

Language:

english

File:

PDF, 648 KB

english, 2008

2

New lessons in the regulation of glucose metabolism taught by the glucose 6-phosphatase system

Gérald van de Werve, Alex Lange, Christopher Newgard, Marie-Claire Méchin, Yazhou Li, Alfred Berteloot

Journal:

Year:

2000

Language:

english

File:

PDF, 1.09 MB

english, 2000

3

10.1038/35093050

Yoon, J. Cliff, Puigserver, Pere, Chen, Guoxun, Donovan, Jerry, Wu, Zhidan, Rhee, James, Adelmant, Guillaume, Stafford, John, Kahn, C. Ronald, Granner, Daryl K., Newgard, Christopher B., Spiegelman, B

Journal:

Year:

2001

Language:

english

File:

PDF, 298 KB

english, 2001

4

A novel leptin receptor isoform in rat

May-Yun Wang, Ting Zhou Yan, Christopher B. Newgard, Roger H. Unger

Journal:

Year:

1996

Language:

english

File:

PDF, 467 KB

english, 1996

5

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

Timothy R. Koves, John R. Ussher, Robert C. Noland, Dorothy Slentz, Merrie Mosedale, Olga Ilkayeva, James Bain, Robert Stevens, Jason R.B. Dyck, Christopher B. Newgard, Gary D. Lopaschuk, Deborah M. M

Journal:

Cell Metabolism

Year:

2008

Language:

english

File:

PDF, 1.00 MB

english, 2008

6

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

Christopher B. Newgard, Jie An, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Lillian F. Lien, Andrea M. Haqq, Svati H. Shah, Michelle Arlotto, Cris A. Slentz, James Rochon, Dianne Gallup,

Journal:

Cell Metabolism

Year:

2009

Language:

english

File:

PDF, 1.19 MB

english, 2009

7

The Problem of Establishing Relationships between Hepatic Steatosis and Hepatic Insulin Resistance

Robert V. Farese Jr., Rudolf Zechner, Christopher B. Newgard, Tobias C. Walther

Journal:

Cell Metabolism

Year:

2012

Language:

english

File:

PDF, 101 KB

english, 2012

8

Severe Acute Malnutrition in Childhood: Hormonal and Metabolic Status at Presentation, Response to Treatment, and Predictors of Mortality

Bartz, Sarah, Mody, Aaloke, Hornik, Christoph, Bain, James, Muehlbauer, Michael, Kiyimba, Tonny, Kiboneka, Elizabeth, Stevens, Robert, Bartlett, John, St Peter, John V., Newgard, Christopher B., Freem

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2014

Language:

english

File:

PDF, 796 KB

english, 2014

9

Obesity-Related Derangements in Metabolic Regulation

Muoio, Deborah M., Newgard, Christopher B.

Journal:

Annual Review of Biochemistry

Year:

2006

Language:

english

File:

PDF, 367 KB

english, 2006

10

Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Responses to Diet Interventions

Griffin, Nicholas W., Ahern, Philip P., Cheng, Jiye, Heath, Andrew C., Ilkayeva, Olga, Newgard, Christopher B., Fontana, Luigi, Gordon, Jeffrey I.

Journal:

Cell Host & Microbe

Year:

2017

Language:

english

File:

PDF, 2.85 MB

english, 2017

11

Sildenafil Treatment in Heart Failure With Preserved Ejection Fraction

Wang, Hanghang, Anstrom, Kevin, Ilkayeva, Olga, Muehlbauer, Michael J., Bain, James R., McNulty, Steven, Newgard, Christopher B., Kraus, William E., Hernandez, Adrian, Felker, G. Michael, Redfield, Ma

Journal:

JAMA Cardiology

Year:

2017

Language:

english

File:

PDF, 141 KB

english, 2017

12

Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men

Ribel‐Madsen, Amalie, Ribel‐Madsen, Rasmus, Brøns, Charlotte, Newgard, Christopher B., Vaag, Allan A., Hellgren, Lars I.

Journal:

Physiological Reports

Year:

2016

Language:

english

File:

PDF, 357 KB

english, 2016

13

Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia

Buettner, Roland, Newgard, Christopher B., Rhodes, Christopher J., O'Doherty, Robert M.

Journal:

American Journal of Physiology-Endocrinology and Metabolism

Year:

2000

Language:

english

File:

PDF, 149 KB

english, 2000

14

The On-Call Crisis: A Statewide Assessment of the Costs of Providing On-Call Specialist Coverage

K. John McConnell, Loren A. Johnson, Nadia Arab, Christopher F. Richards, Craig D. Newgard, Tina Edlund

Journal:

Annals of Emergency Medicine

Year:

2007

Language:

english

File:

PDF, 429 KB

english, 2007

15

Chemical Knockout of Pantothenate Kinase Reveals the Metabolic and Genetic Program Responsible for Hepatic Coenzyme A Homeostasis

Yong-Mei Zhang, Shigeru Chohnan, Kristopher G. Virga, Robert D. Stevens, Olga R. Ilkayeva, Brett R. Wenner, James R. Bain, Christopher B. Newgard, Richard E. Lee, Charles O. Rock, Suzanne Jackowski

Journal:

Chemistry & Biology

Year:

2007

Language:

english

File:

PDF, 1.53 MB

english, 2007

16

Modeling the biochemical differences between rabbit muscle and human liver phosphorylase

Virginia L. Rath, Christopher B. Newgard, Stephen R. Sprang, Elizabeth J. Goldsmith, Robert J. Fletterick

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1987

Language:

english

File:

PDF, 1.10 MB

english, 1987

17

Understanding of basic mechanisms of β-cell function and survival

Christopher B. Newgard, Hans E. Hohmeier, Danhong Lu, Mette Valentin Jensen, Veronique V. Tran, Guoxun Chen, Shawn Burgess, A. Dean Sherry

Journal:

Cell Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 809 KB

english, 2004

18

Altered distribution of adiponectin isoforms in children with Prader–Willi syndrome (PWS): association with insulin sensitivity and circulating satiety peptide hormones

Andrea M. Haqq, Michael Muehlbauer, Laura P. Svetkey, Christopher B. Newgard, Jonathan Q. Purnell, Steven C. Grambow, Michael S. Freemark

Journal:

Clinical Endocrinology

Year:

2007

Language:

english

File:

PDF, 264 KB

english, 2007

19

Ghrelin concentrations in Prader–Willi syndrome (PWS) infants and children: changes during development

Andrea M. Haqq, Steven C. Grambow, Michael Muehlbauer, Christopher B. Newgard, Laura P. Svetkey, Aaron L. Carrel, Jack A. Yanovski, Jonathan Q. Purnell, Michael Freemark

Journal:

Clinical Endocrinology

Year:

2008

Language:

english

File:

PDF, 210 KB

english, 2008

20

Metabolism: A is for adipokine

Muoio, Deborah M., Newgard, Christopher B.

Journal:

Year:

2005

Language:

english

File:

PDF, 382 KB

english, 2005

21

Islets for all?

Hohmeier, Hans E, Newgard, Christopher B

Journal:

Nature Biotechnology

Year:

2005

Language:

english

File:

PDF, 143 KB

english, 2005

22

Getting biological about the genetics of diabetes

Newgard, Christopher B, Attie, Alan D

Journal:

Nature Medicine

Year:

2010

Language:

english

File:

PDF, 530 KB

english, 2010

23

A futile metabolic cycle activated in adipocytes by antidiabetic agents

Newgard, Christopher B., Steppan, Claire M., Lazar, Mitchell A., Guan, Hong-Ping, Li, Yong, Jensen, Mette Valentin

Journal:

Nature Medicine

Year:

2002

Language:

english

File:

PDF, 1.19 MB

english, 2002

24

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

An, Jie, Muoio, Deborah M, Shiota, Masakazu, Fujimoto, Yuka, Cline, Gary W, Shulman, Gerald I, Koves, Timothy R, Stevens, Robert, Millington, David, Newgard, Christopher B

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 759 KB

english, 2004

25

Understanding of basic mechanisms of β-cell function and survival

Christopher B. Newgard, Hans E. Hohmeier, Danhong Lu, Mette Valentin Jensen, Veronique V. Tran, Guoxun Chen, Shawn Burgess, A. Dean Sherry

Journal:

Cell Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 195 KB

english, 2004

26

Daily variation of serum acylcarnitines and amino acids

Thompson, Dana K., Sloane, Richard, Bain, James R., Stevens, Robert D., Newgard, Christopher B., Pieper, Carl F., Kraus, Virginia B.

Journal:

Year:

2012

Language:

english

File:

PDF, 352 KB

english, 2012

27

Metabolic profiles predict adverse events after coronary artery bypass grafting

Asad A. Shah, Damian M. Craig, Jacqueline K. Sebek, Carol Haynes, Robert C. Stevens, Michael J. Muehlbauer, Christopher B. Granger, Elizabeth R. Hauser, L. Kristin Newby, Christopher B. Newgard, Willi

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2012

Language:

english

File:

PDF, 245 KB

english, 2012

28

Lessons from the bioengineered β-cell

Christopher B. Newgard

Journal:

Journal of Diabetes and its Complications

Year:

2001

Language:

english

File:

PDF, 44 KB

english, 2001

29

Finding mechanisms from metabolic signatures of disease

Newgard, Christopher B

Journal:

BMC Proceedings

Year:

2012

Language:

english

File:

PDF, 164 KB

english, 2012

30

Snare Protein Expression and Adenoviral Transfection of Amphicrine AR42J

Herbert Y. Gaisano, Xiaohang Huang, Laura Sheu, Menisha Ghai, Christopher B. Newgard, Khiet Y. Trinh, William S. Trimble

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 77 KB

english, 1999

31

Analysis of the protein products encoded by variant glucokinase transcripts via expression in bacteria

Christian Quaade, Steven D. Hughes, Ward S. Coats, Andrea L. Sestak, Patrick B. Iynedjian, Christopher B. Newgard

Journal:

Year:

1991

Language:

english

File:

PDF, 802 KB

english, 1991

32

Hyperlipidemic Effects of Dietary Saturated Fats Mediated through PGC-1β Coactivation of SREBP

Jiandie Lin, Ruojing Yang, Paul T. Tarr, Pei-Hsuan Wu, Christoph Handschin, Siming Li, Wenli Yang, Liming Pei, Marc Uldry, Peter Tontonoz, Christopher B. Newgard, Bruce M. Spiegelman

Journal:

Year:

2005

Language:

english

File:

PDF, 761 KB

english, 2005

33

Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver

Mara Monetti, Malin C. Levin, Matthew J. Watt, Mini P. Sajan, Stephen Marmor, Brian K. Hubbard, Robert D. Stevens, James R. Bain, Christopher B. Newgard, Robert V. Farese Sr., Andrea L. Hevener, Rober

Journal:

Cell Metabolism

Year:

2007

Language:

english

File:

PDF, 661 KB

english, 2007

34

The Liver—A Potential New Player in Islet Regeneration?

Larry G. Moss, Christopher B. Newgard

Journal:

Cell Metabolism

Year:

2009

Language:

english

File:

PDF, 121 KB

english, 2009

35

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

Christopher B. Newgard, Jie An, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Lillian F. Lien, Andrea M. Haqq, Svati H. Shah, Michelle Arlotto, Cris A. Slentz, James Rochon, Dianne Gallup,

Journal:

Cell Metabolism

Year:

2009

Language:

english

File:

PDF, 85 KB

english, 2009

36

Regulation of Skeletal Muscle Oxidative Capacity and Insulin Signaling by the Mitochondrial Rhomboid Protease PARL

Anthony E. Civitarese, Paul S. MacLean, Stacy Carling, Lyndal Kerr-Bayles, Ryan P. McMillan, Anson Pierce, Thomas C. Becker, Cedric Moro, Jean Finlayson, Natalie Lefort, Christopher B. Newgard, Lawren

Journal:

Cell Metabolism

Year:

2010

Language:

english

File:

PDF, 1.75 MB

english, 2010

37

Branching Out for Detection of Type 2 Diabetes

Svati H. Shah, Laura P. Svetkey, Christopher B. Newgard

Journal:

Cell Metabolism

Year:

2011

Language:

english

File:

PDF, 253 KB

english, 2011

38

A VGF-Derived Peptide Attenuates Development of Type 2 Diabetes via Enhancement of Islet β-Cell Survival and Function

Samuel B. Stephens, Jonathan C. Schisler, Hans E. Hohmeier, Jie An, Albert Y. Sun, Geoffrey S. Pitt, Christopher B. Newgard

Journal:

Cell Metabolism

Year:

2012

Language:

english

File:

PDF, 671 KB

english, 2012

39

Cell lines derived from pancreatic islets

Hans E. Hohmeier, Christopher B. Newgard

Journal:

Molecular and Cellular Endocrinology

Year:

2004

Language:

english

File:

PDF, 177 KB

english, 2004

40

Gp93, the Drosophila GRP94 ortholog, is required for gut epithelial homeostasis and nutrient assimilation-coupled growth control

Jason C. Maynard, Trang Pham, Tianli Zheng, Angela Jockheck-Clark, Helen B. Rankin, Christopher B. Newgard, Eric P. Spana, Christopher V. Nicchitta

Journal:

Developmental Biology

Year:

2010

Language:

english

File:

PDF, 1.73 MB

english, 2010

41

Suppression of β Cell Energy Metabolism and Insulin Release by PGC-1α

J.Cliff Yoon, Gang Xu, Jude T Deeney, Shao-Nian Yang, James Rhee, Pere Puigserver, Adah R Levens, Ruojing Yang, Chen-Yu Zhang, Bradford B Lowell, Per-Olof Berggren, Christopher B Newgard, Susan Bonner

Journal:

Developmental Cell

Year:

2003

Language:

english

File:

PDF, 625 KB

english, 2003

42

Cafeteria Diet Is a Robust Model of Human Metabolic Syndrome With Liver and Adipose Inflammation: Comparison to High-Fat Diet

Brante P. Sampey, Amanda M. Vanhoose, Helena M. Winfield, Alex J. Freemerman, Michael J. Muehlbauer, Patrick T. Fueger, Christopher B. Newgard, Liza Makowski

Journal:

Year:

2011

Language:

english

File:

PDF, 698 KB

english, 2011

43

Glucokinase gene transfer to skeletal muscle of diabetic Zucker fatty rats improves insulin-sensitive glucose uptake

Josep C. Jim[eacute]nez-Chillar[oacute]n, Sabine Telemaque-Potts, Al[iacute]cia G. G[oacute]mez-Valad[eacute]s, Paul Anderson, Christopher B. Newgard, Anna M. G[oacute]mez-Foix

Journal:

Year:

2002

Language:

english

File:

PDF, 238 KB

english, 2002

44

Expression of reg /PSP, a Pancreatic Exocrine Gene: Relationship to Changes in Islet β-Cell Mass

Miyaura, Chisato, Chen, Ling, Appel, Michael, Alam, Tausif, Inman, Lindsey, Hughes, Steven D., Milburn, Joseph L., Unger, Roger H., Newgard, Christopher B.

Journal:

Molecular Endocrinology

Year:

1991

Language:

english

File:

PDF, 2.33 MB

english, 1991

45

Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance

Christopher B. Newgard

Journal:

Cell Metabolism

Year:

2012

Language:

english

File:

PDF, 817 KB

english, 2012

46

225 THE EFFECTS OF CHOLESTEROL TREATMENT DRUGS ALONE AND IN COMBINATION ON PROSTATE TUMOR XENOGRAFT GROWTH

Masko, Elizabeth M., Solomon, Keith R., Valilis, Nikolaos A., Gaines, Alexis R., Muehlbauer, Michael J., Newgard, Christopher B., Dewhirst, Mark W., Pizzo, Salvatore V., Freedland, Stephen J.

Journal:

The Journal of Urology

Year:

2012

Language:

english

File:

PDF, 50 KB

english, 2012

47

INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN (IGFBP) 2: A NOVEL METABOLIC BIOMARKER STRONGLY PREDICTIVE OF FUTURE CARDIOVASCULAR EVENTS

Svati Hasmukh Shah, Jie-Lena Sun, Karen Pieper, Carol Haynes, Michael Muehlbauer, James R. Bain, Elizabeth R. Hauser, William E. Kraus, Christopher B. Newgard, Christopher B. Granger, Robert M. Califf

Journal:

Journal of the American College of Cardiology

Year:

2010

Language:

english

File:

PDF, 62 KB

english, 2010

48

Structure of Mammalian Isozymes of Glycogen Phosphorylase : Implications for Function

CHRISTOPHER B. NEWGARD, KENICHI NAKANO, PETER K. HWANG, ROBERT J. FLETTERICK

Journal:

Annals of the New York Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 100 KB

english, 1986

49

Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness

Batch, Bryan C., Shah, Svati H., Newgard, Christopher B., Turer, Christy B., Haynes, Carol, Bain, James R., Muehlbauer, Michael, Patel, Mahesh J., Stevens, Robert D., Appel, Lawrence J., Newby, L. Kri

Journal:

Year:

2013

Language:

english

File:

PDF, 242 KB

english, 2013

50

Application of combined omics platforms to accelerate biomedical discovery in diabesity

Kurland, Irwin J., Accili, Domenico, Burant, Charles, Fischer, Steven M., Kahn, Barbara B., Newgard, Christopher B., Ramagiri, Suma, Ronnett, Gabriele V., Ryals, John A., Sanders, Mark, Shambaugh, Joe

Journal:

Annals of the New York Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 976 KB

english, 2013